NAD+
A central redox coenzyme studied in mitochondrial metabolism, electron-transfer biology, sirtuin/PARP-associated pathways, and cellular energy research.
Purity Verified by COA
Research Use Only
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Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
NAD+
- CAS number
- 53-84-9
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.43 g/mol
- Form
- Lyophilized powder
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
NAD-related metabolites during infusion
PUBMED · PMID 31572171A small uncontrolled human infusion pilot measured plasma and urinary NAD-related metabolites over eight hours; it did not test clinical efficacy.
Open original source Verified identity recordNAD+ compound identity
PUBCHEM | CID 5892PubChem provides the public compound identity and structure record. Lot-specific form and purity must still be confirmed against the batch documentation.
Open identity record Live literature indexBrowse PubMed for NAD+
PUBMED | LIVE SEARCHThis opens a live literature search. Results can concern other formulations and do not test this product or batch.
Browse literature indexResearch overview
NAD+ is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is NAD+?
NAD+ is a central redox coenzyme involved in electron-transfer reactions and cellular metabolism. In research settings, it is used to study mitochondrial function, redox balance, and enzyme systems that depend on NAD availability.
NAD+ is not a peptide, but it is frequently included in research-compound catalogs because of its relevance to cellular energy and metabolic biology.
Mechanism of Action / Research Focus
NAD+ participates in oxidation-reduction reactions by cycling between oxidized and reduced forms. It is also connected to enzyme systems such as sirtuins and PARPs, making it relevant to studies of DNA repair, stress response, and metabolic regulation.
Researchers use NAD+ in biochemical and cellular assays where redox state, mitochondrial function, and cofactor availability are key variables.
Common Research Applications
Application Areas
- Redox biology and mitochondrial metabolism
- Sirtuin/PARP-associated pathway assays
- DNA-repair and cellular stress-response research
- Cellular energy and coenzyme models
Research Comparison
| Research tool | Primary focus | Research endpoint examples |
|---|---|---|
| SS-31 | Cardiolipin and inner mitochondrial membrane biology. | Respiration, oxidative stress, mitochondrial energetics. |
| MOTS-c | Mitochondrial-derived peptide signaling. | Mitonuclear communication, AMPK-associated signaling, metabolic stress. |
| NAD+ | Redox coenzyme and NAD-dependent enzyme systems. | NAD+/NADH balance, sirtuin/PARP pathways, cellular energy. |
| Glutathione | Thiol redox and antioxidant defense. | GSH/GSSG ratios, ROS response, detoxification pathways. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
NAD+ FAQs
Is NAD+ a peptide?
No. NAD+ is a nucleotide coenzyme, not a peptide.
Why is it in the catalog?
It supports research workflows involving mitochondrial metabolism, redox biology, and cellular energy.
Is this for injection or supplementation?
No. It is supplied strictly for laboratory research use.
Selected Research & Chemical References
Chemical Information
| Product | NAD+ |
|---|---|
| Synonyms | Nicotinamide adenine dinucleotide; oxidized NAD |
| CAS Number | 53-84-9 |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.43 g/mol |
| Form | Lyophilized powder |
| Contents | 500mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.
