Ipamorelin
A growth hormone secretagogue peptide studied in ghrelin receptor signaling, pituitary response, GH/IGF-1 axis models, and endocrine receptor-selectivity research.
Purity Verified by COA
Research Use Only
In stock
- Cards & debit
- Apple Pay
- Google Pay
- Link
- ACH when available
Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
Ipamorelin
- CAS number
- 170851-70-4
- Molecular formula
- C38H49N9O5
- Molecular weight
- 711.853 g/mol
- Form
- Lyophilized powder
- Sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
Ipamorelin, the first selective growth hormone secretagogue
Eur J Endocrinol · 1998 · PMID 9849822In vitro and animal models characterized growth-hormone release through a GHRP-like receptor pathway.
Open original source Human PK/PD studyPharmacokinetic-pharmacodynamic modeling of ipamorelin
Pharm Res · 1999 · PMID 10496658A dose-escalation study in healthy male volunteers modeled plasma disposition and the time course of GH response.
Open original source Phase 2 randomized trialIpamorelin for postoperative ileus after bowel resection
Int J Colorectal Dis · 2014 · PMID 25331030The proof-of-concept trial reported no significant difference from placebo in its key or secondary efficacy analyses.
Open original sourceResearch overview
Ipamorelin is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide commonly studied as a growth hormone secretagogue and ghrelin receptor pathway research tool.
It is used in controlled endocrine models involving pituitary response, GH/IGF-1 axis signaling, receptor selectivity, and comparative secretagogue research.
Mechanism of Action / Research Focus
Ipamorelin is studied for interaction with the ghrelin receptor/growth hormone secretagogue receptor pathway. In experimental models, this receptor system is connected to pituitary growth hormone response and downstream endocrine signaling.
Compared with broader endocrine compounds, ipamorelin is valued in research for receptor-selectivity questions and GH-axis experimental design.
Common Research Applications
Application Areas
- Ghrelin-receptor and GHSR signaling studies
- GH-axis and pituitary-response assays
- Peptide receptor selectivity research
- Comparative studies with GHRH analogs
Research Comparison
| Research tool | Primary pathway | Common research purpose |
|---|---|---|
| Sermorelin | GHRH receptor signaling. | GHRH(1–29), pituitary response, and GH/IGF-1 axis research. |
| Tesamorelin | GHRH receptor signaling. | GHRH analog research with metabolic/endocrine endpoints. |
| Ipamorelin | Ghrelin receptor / GHSR signaling. | Growth hormone secretagogue and receptor-selectivity research. |
| CJC-1295 + Ipamorelin | GHRH + GHSR pathways. | Blend-based GH-axis and pituitary signaling research. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
Ipamorelin FAQs
What pathway is Ipamorelin commonly studied in?
The ghrelin receptor/growth hormone secretagogue pathway.
Is Ipamorelin for human use?
No. It is supplied strictly for laboratory research.
How is it different from Sermorelin?
Sermorelin is studied as a GHRH analog, while ipamorelin is studied as a ghrelin receptor/GHSR pathway peptide.
Selected Research & Chemical References
Chemical Information
| Product | Ipamorelin |
|---|---|
| Synonyms | Growth hormone secretagogue; ghrelin receptor agonist research peptide |
| CAS Number | 170851-70-4 |
| Molecular Formula | C38H49N9O5 |
| Molecular Weight | 711.853 g/mol |
| Form | Lyophilized powder |
| Contents | 5mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.
