Semax
A synthetic ACTH(4–10)-derived heptapeptide studied in neurotrophic signaling, BDNF-associated pathways, neuroprotection models, and cognitive research.
Purity Verified by COA
Research Use Only
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Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
Semax
- CAS number
- 80714-61-0
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.92 g/mol
- Form
- Lyophilized powder
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
Semax after ischemic stroke
PUBMED · PMID 29798983A rehabilitation study reported BDNF and functional-score changes in treated and untreated subgroups; the design limits causal interpretation.
Open original source Verified identity recordSemax compound identity
PUBCHEM | CID 9811102PubChem provides the public compound identity and structure record. Lot-specific form and purity must still be confirmed against the batch documentation.
Open identity record Live literature indexBrowse PubMed for Semax
PUBMED | LIVE SEARCHThis opens a live literature search. Results can concern other formulations and do not test this product or batch.
Browse literature indexResearch overview
Semax is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is Semax?
Semax is a synthetic heptapeptide derived from the ACTH(4–10) fragment and commonly studied in neurobiology research.
It is used in models evaluating neurotrophic signaling, BDNF/TrkB-associated pathways, stress response, memory/learning endpoints, and neuronal survival.
Mechanism of Action / Research Focus
Semax research often focuses on neuropeptide signaling, neurotrophic factor expression, melanocortin-related biology, and protection against experimental neuronal stress.
Researchers also evaluate Semax in comparison with Selank and other neuropeptide tools in models of learning, memory, and neuroplasticity.
Common Research Applications
Application Areas
- Neurotrophic signaling research
- Stress-response pathway assays
- Cognitive-model and neurobiology studies
- ACTH-fragment analog research
Research Comparison
| Research compound | Primary research focus | Useful comparison |
|---|---|---|
| Semax | Neurotrophic signaling, BDNF/TrkB-associated pathways, cognitive models. | Compare with Selank for neuropeptide signaling differences. |
| Selank | GABAergic, neuroimmune, cytokine, and stress-response models. | Compare with Semax in neuroplasticity and stress paradigms. |
| DSIP | Sleep-state, neuroendocrine, and peptide neuromodulation research. | Requires carefully defined endpoints due to mixed literature. |
| Dihexa | HGF/c-Met-associated synaptogenesis and neuroplasticity research. | Small peptide-like compound rather than a classic vial peptide. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
Semax FAQs
What is Semax derived from?
Semax is derived from the ACTH(4–10) peptide fragment.
Is Semax approved for consumer use by Aqua Biolabs?
No. It is provided solely for laboratory research.
How should it be compared with Selank?
Use clearly defined neurobiology endpoints and separate controls for each compound.
Selected Research & Chemical References
Chemical Information
| Product | Semax |
|---|---|
| Synonyms | Met-Glu-His-Phe-Pro-Gly-Pro heptapeptide |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| CAS Number | 80714-61-0 |
| Molecular Formula | C37H51N9O10S |
| Molecular Weight | 813.92 g/mol |
| Form | Lyophilized powder |
| Contents | 10mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.
