TB-500 Fragment
A thymosin beta-4 fragment research peptide studied in actin-binding biology, cytoskeletal organization, cell migration, and tissue-remodeling models.
Purity Verified by COA
Research Use Only
Out of stock
Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
TB-500 Fragment
- CAS number
- 885340-08-9
- Molecular formula
- C38H68N10O14
- Molecular weight
- 889.0 g/mol
- Form
- Lyophilized powder
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
FDA review of the TB-500 fragment
FDA PCAC BRIEFING - exact-fragment evidence reviewThe review identifies the commonly referenced fragment as Ac-LKKTETQ-OH and reports that it found no in-vivo wound-healing study on exact TB-500 and no human exposure data.
Open original source PubChem identity recordPubChem TB-500 fragment record
PUBCHEM.NCBI.NLM.NIH.GOVReview the original source for its methods, study population or model, endpoints, limitations, and reported findings.
Open original source Verified identity recordTB-500 Fragment compound identity
PUBCHEM | CID 62707662PubChem provides the public compound identity and structure record. Lot-specific form and purity must still be confirmed against the batch documentation.
Open identity recordResearch overview
TB-500 Fragment is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is TB-500 Fragment?
TB-500 Fragment is a defined fragment associated with thymosin beta-4 research. It is commonly evaluated in models that focus on actin binding, cell motility, cytoskeletal remodeling, and extracellular-matrix response.
Fragment products should be documented carefully because sequence, salt form, and purity can influence cross-study comparisons.
Mechanism of Action / Research Focus
The fragment is used to isolate thymosin beta-4–associated research pathways without representing the full-length peptide. Research contexts include cytoskeletal signaling, cell migration, endothelial response, and remodeling assays.
Researchers should confirm fragment identity and lot-specific analytical documentation before interpreting results.
Common Research Applications
Application Areas
- Actin polymerization and cell-motility assays
- Angiogenesis-related research
- Tissue-remodeling models
- Fragment-level studies distinct from full-length thymosin beta-4
Research Comparison
| Research tool | Common pathway focus | Typical model type |
|---|---|---|
| BPC-157 | Fibroblast, nitric oxide, angiogenesis-associated, and ECM signaling. | Barrier, tissue-remodeling, and soft-tissue research models. |
| TB-500 / fragment | Actin, cytoskeletal organization, and cell migration. | Cell motility, endothelial, and remodeling assays. |
| GHK-Cu | Copper-peptide and extracellular-matrix signaling. | Collagen-associated and dermatological research models. |
| KPV | Inflammatory and barrier-signaling pathways. | Epithelial, cytokine, and immune-barrier models. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
TB-500 Fragment FAQs
Why is this listed separately from TB-500?
This entry emphasizes fragment identity and should be matched to the COA before research use.
Is the formula universal?
Formula and molecular weight can depend on sequence and salt form; verify against the lot COA.
Is this product for human use?
No. It is for laboratory research only.
Selected Research & Chemical References
Chemical Information
| Product | TB-500 Fragment |
|---|---|
| Synonyms | TB-500 fragment; thymosin beta-4 active-region research peptide |
| CAS Number | 885340-08-9 |
| Molecular Formula | C38H68N10O14 |
| Molecular Weight | 889.0 g/mol |
| Form | Lyophilized powder |
| Contents | 5mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.




