Tirzepatide
A dual GIP/GLP-1 receptor agonist peptide studied in incretin biology, glucose-response models, insulin signaling, and metabolic regulation research.
Purity Verified by COA
Research Use Only
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Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
Tirzepatide
- CAS number
- 2023788-19-2
- Molecular formula
- C225H348N48O68
- Molecular weight
- 4813 g/mol
- Form
- Lyophilized powder
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
Tirzepatide in adults with obesity
PUBMED · PMID 35658024The SURMOUNT-1 trial of a pharmaceutical tirzepatide formulation reported dose-related weight reductions and frequent gastrointestinal adverse events.
Open original source PubChem identity recordPubChem tirzepatide record
PUBCHEM.NCBI.NLM.NIH.GOVReview the original source for its methods, study population or model, endpoints, limitations, and reported findings.
Open original source Peer-reviewed publicationDual GIP/GLP-1 receptor agonist clinical pharmacology
DOI.ORGReview the original source for its methods, study population or model, endpoints, limitations, and reported findings.
Open original sourceResearch overview
Tirzepatide is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is Tirzepatide?
Tirzepatide is a synthetic peptide research analog designed to engage both GIP and GLP-1 receptor pathways. This dual-incretin profile makes it useful for studying complementary receptor effects in glucose and energy-balance models.
Compared with GLP-1-only research compounds, tirzepatide allows investigators to evaluate how GIP and GLP-1 signaling may interact in endocrine, metabolic, and adipose-tissue research contexts.
Mechanism of Action / Research Focus
Tirzepatide is studied as a dual agonist of the GIP and GLP-1 receptors. In research systems, GLP-1 receptor engagement is commonly associated with glucose-dependent insulin response, glucagon modulation, and appetite-signaling endpoints; GIP receptor engagement adds another incretin axis involved in insulin response and metabolic signaling.
This dual activity is relevant in experiments comparing single-pathway GLP-1 agonism with broader incretin receptor engagement.
Common Research Applications
Application Areas
- Dual GIP/GLP-1 receptor pharmacology
- Incretin signaling and metabolic regulation
- Glucose-handling and insulin-response research models
- Comparative studies with semaglutide and retatrutide
Research Comparison
| Research compound | Primary receptor focus | Common research context |
|---|---|---|
| Semaglutide | GLP-1 | Single-incretin pathway research; glucose and appetite-signaling models. |
| Tirzepatide | GIP + GLP-1 | Dual-incretin research; insulin-response and metabolic regulation models. |
| Retatrutide | GIP + GLP-1 + glucagon | Triple-pathway research; energy balance, body-composition, and hepatic/metabolic endpoints. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
Tirzepatide FAQs
Is Tirzepatide sold here for clinical use?
No. This product is for laboratory research use only and is not for human or veterinary use.
What receptor systems are commonly studied?
Tirzepatide is commonly studied in relation to GIP and GLP-1 receptor signaling.
What documentation should researchers check?
Check product label, SKU, fill amount, batch/lot number, COA documentation, and storage requirements.
Selected Research & Chemical References
Chemical Information
| Product | Tirzepatide |
|---|---|
| Synonyms | LY3298176; dual GIP/GLP-1 receptor agonist research analog |
| CAS Number | 2023788-19-2 |
| Molecular Formula | C225H348N48O68 |
| Molecular Weight | 4813 g/mol |
| Form | Lyophilized powder |
| Contents | 10mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.




