Dihexa
An angiotensin IV–derived research compound studied in HGF/c-Met-associated signaling, synaptogenesis models, neuroplasticity, and cognitive research.
Purity Verified by COA
Research Use Only
In stock
- Cards & debit
- Apple Pay
- Google Pay
- Link
- ACH when available
Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
Dihexa
- CAS number
- 1401708-83-5
- Molecular formula
- C27H44N4O5
- Molecular weight
- 504.662 g/mol
- Form
- Lyophilized powder
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
Dihexa in an APP/PS1 mouse model
PUBMED · PMID 34827486In APP/PS1 mice, Dihexa exposure was associated with behavioral, neuronal, and PI3K/AKT-pathway measures.
Open original source Verified identity recordDihexa compound identity
PUBCHEM | CID 129010512PubChem provides the public compound identity and structure record. Lot-specific form and purity must still be confirmed against the batch documentation.
Open identity record Live literature indexBrowse PubMed for Dihexa
PUBMED | LIVE SEARCHThis opens a live literature search. Results can concern other formulations and do not test this product or batch.
Browse literature indexResearch overview
Dihexa is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is Dihexa?
Dihexa is an angiotensin IV–derived small peptide-like research compound studied in neuroplasticity and synaptogenesis models.
It is commonly discussed in relation to HGF/c-Met pathway research and experimental models of synaptic connectivity and cognitive function.
Mechanism of Action / Research Focus
Dihexa research focuses on signaling pathways associated with hepatocyte growth factor (HGF) and c-Met, with interest in synaptogenesis, dendritic spine formation, and neuroplasticity endpoints.
Because it is highly potent in some experimental systems, careful concentration control, documentation, and appropriate controls are essential.
Common Research Applications
Application Areas
- HGF/c-Met pathway research
- Synaptogenesis and neurotrophic models
- Cognitive biology assays
- Angiotensin IV analog studies
Research Comparison
| Research compound | Primary research focus | Useful comparison |
|---|---|---|
| Semax | Neurotrophic signaling, BDNF/TrkB-associated pathways, cognitive models. | Compare with Selank for neuropeptide signaling differences. |
| Selank | GABAergic, neuroimmune, cytokine, and stress-response models. | Compare with Semax in neuroplasticity and stress paradigms. |
| DSIP | Sleep-state, neuroendocrine, and peptide neuromodulation research. | Requires carefully defined endpoints due to mixed literature. |
| Dihexa | HGF/c-Met-associated synaptogenesis and neuroplasticity research. | Small peptide-like compound rather than a classic vial peptide. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
Dihexa FAQs
Is Dihexa a peptide?
It is often described as an angiotensin IV–derived peptide-like research compound.
Is Dihexa for human use?
No. It is provided strictly for laboratory research.
What documentation matters?
Identity, purity, salt/form, and lot-specific analytical data.
Selected Research & Chemical References
Chemical Information
| Product | Dihexa |
|---|---|
| Synonyms | PNB-0408; angiotensin IV analog research compound |
| CAS Number | 1401708-83-5 |
| Molecular Formula | C27H44N4O5 |
| Molecular Weight | 504.662 g/mol |
| Form | Lyophilized powder |
| Contents | 10mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.




