SS-31
A mitochondria-targeted tetrapeptide studied in cardiolipin interaction, inner mitochondrial membrane biology, oxidative-stress signaling, and cellular bioenergetics research.
Purity Verified by COA
Research Use Only
- Cards & debit
- Apple Pay
- Google Pay
- Link
- ACH when available
Research at a glance
Stable compound identity and handling reference. Confirm lot-specific values against the vial label and available batch record.
SS-31
- CAS number
- 736992-21-5
- Molecular formula
- C32H49N9O5
- Molecular weight
- 639.79 g/mol
- Form
- Lyophilized powder
Storage
Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol.
Lot-specific records
Batch-specific - verify availability in the COA library
Open COA librarySelected research sources
Curated literature, verified identity records, and clearly labeled live indexes for the named compound or formulation. None tests this batch or establishes an intended use.
Membrane-interface interactions of elamipretide
PUBMED · PMID 32273339Biophysical and computational experiments found membrane-interface binding that varied with lipid charge and altered surface electrostatics.
Open original source PubChem identity recordPubChem elamipretide record
PUBCHEM.NCBI.NLM.NIH.GOVReview the original source for its methods, study population or model, endpoints, limitations, and reported findings.
Open original source Verified identity recordSS-31 compound identity
PUBCHEM | CID 11764719PubChem provides the public compound identity and structure record. Lot-specific form and purity must still be confirmed against the batch documentation.
Open identity recordResearch overview
SS-31 is supplied as a research-grade material for qualified laboratory use only.
Batch-specific documentation should be reviewed before use. Match vial label, fill amount, SKU, and lot number to the corresponding COA documentation.
Description
What is SS-31?
SS-31, also known as elamipretide, is a small mitochondria-targeting tetrapeptide used in research on inner mitochondrial membrane biology and cardiolipin-associated interactions.
Its compact aromatic-cationic structure is frequently discussed in relation to mitochondrial membrane localization, oxidative-stress endpoints, and cellular bioenergetic measurements.
Mechanism of Action / Research Focus
SS-31 is studied for its association with cardiolipin, a phospholipid enriched in the inner mitochondrial membrane. This interaction is relevant to research on electron transport chain organization, mitochondrial membrane dynamics, and reactive oxygen species signaling.
In experimental models, SS-31 is used to examine mitochondrial stress response, ATP-associated endpoints, cellular respiration, and tissue-specific mitochondrial function.
Common Research Applications
Application Areas
- Mitochondrial membrane and cardiolipin-associated studies
- Oxidative-stress and reactive oxygen species models
- Cellular bioenergetics and ATP-associated assays
- Cardiac, skeletal muscle, and neurobiology research models
Research Comparison
| Research tool | Primary focus | Research endpoint examples |
|---|---|---|
| SS-31 | Cardiolipin and inner mitochondrial membrane biology. | Respiration, oxidative stress, mitochondrial energetics. |
| MOTS-c | Mitochondrial-derived peptide signaling. | Mitonuclear communication, AMPK-associated signaling, metabolic stress. |
| NAD+ | Redox coenzyme and NAD-dependent enzyme systems. | NAD+/NADH balance, sirtuin/PARP pathways, cellular energy. |
| Glutathione | Thiol redox and antioxidant defense. | GSH/GSSG ratios, ROS response, detoxification pathways. |
Certificate of Analysis (COA)
Applicable lots should be supported by batch-specific analytical documentation. Before beginning work, verify product identity, purity, fill amount, lot number, and storage requirements against the COA and product label.
SS-31 FAQs
What is SS-31 commonly used to study?
Mitochondrial membrane biology, cardiolipin interaction, oxidative-stress pathways, and cellular energy metabolism.
Is SS-31 supplied for therapeutic use?
No. This product is for qualified laboratory research only.
Should salt form be verified?
Yes. Researchers should verify salt form, purity, and identity on the COA.
Selected Research & Chemical References
Chemical Information
| Product | SS-31 |
|---|---|
| Synonyms | Elamipretide; Bendavia; mitochondria-targeting tetrapeptide |
| CAS Number | 736992-21-5 |
| Molecular Formula | C32H49N9O5 |
| Molecular Weight | 639.79 g/mol |
| Form | Lyophilized powder |
| Contents | 10mg, 50mg fill amount(s), supplied as lyophilized powder in sealed research vial format unless otherwise stated on the label. |
| Research Notes | Researchers are responsible for supplying compatible diluent, sterile technique supplies, and protocol-specific materials. Compatibility should be validated before any study. |
| Storage | Store sealed, protected from heat, light, and moisture. For long-term storage, follow the lot-specific COA, label, and institutional protocol. Avoid repeated freeze-thaw cycles after preparation unless validated in the research protocol. |
Shipping Information
Orders are fulfilled from domestic inventory when available. Shipping options, carrier service, and delivery estimates are shown at checkout and are subject to inventory status, cutoff times, weather, holidays, and carrier performance.
For larger research quantities or lot-specific documentation requests, contact Aqua Biolabs support before ordering.
Research Use & Compliance
Aqua Biolabs products are intended for laboratory research use only. Products are not drugs, foods, dietary supplements, cosmetics, medical devices, or consumer products.
Products are not intended for human consumption, injection, veterinary use, diagnostic use, therapeutic use, food use, cosmetic application, or household use. Purchasers are responsible for compliance with all applicable laws, institutional requirements, and research safety protocols.
